BON-WAC
Complete SYSADOA (Symptomatic Slow-Acting Drug for Osteoarthritis) and Dual COX-2/5-LOX Inflammatory Modulator.
Active Clinical Composition: Complete SYSADOA, 5 LOX and COX 2 Inhibitors
₨ 1,180
Complete SYSADOA (Symptomatic Slow-Acting Drug for Osteoarthritis) and Dual COX-2/5-LOX Inflammatory Modulator.
₨ 1,180
BON WAC os a complete SYSADOA (Symptomatic Slow-Acting Drug for Osteoarthritis) and Dual COX-2/5-LOX Inflammatory Modulator.
Mechanism of Action: BON-WAC operates through a Dual-Pathway architecture to restore joint integrity and bypass the pro-inflammatory “NSAID Shunt”:
Pathway A (Structural Matrix / Complete SYSADOA): Halts MMP-driven catabolism and provides direct organic substrates to restore chondrocyte metabolism and synthesize Type II collagen.
Glucosamine Sulphate: Drives glycosaminoglycan (GAG) and hyaluronic acid biosynthesis.
Chondroitin Sulphate: Restores hydraulic fluid retention and competitively suppresses collagenase enzymes.
MSM: Acts as an essential organic sulfur donor required for stable disulfide bond formation.
Pathway B (Inflammatory Modulator): Actively suppresses synovial inflammation without precipitating gastro-hepatic or renal toxicity.
Boswellia Serrata API (AKBA Standardized): Acts as a direct 5-LOX pathway inhibitor, halting pro-inflammatory leukotriene (LTB4) synthesis to rapidly resolve swelling.
Curcumin USP: Intercepts COX-2 cascades to downregulate TNF-α and IL-1β, safely resolving nociceptive pain.
Pharmacokinetics (The Lipid Rule): To guarantee maximum bioavailability, the active botanical extracts (Curcumin and Boswellia) require dietary lipids to maximize lymphatic bypass absorption.
BON-WAC is clinically indicated for the management of joint pathology and structural degradation:
Osteoarthritis (OA) – Stages I–III / Load-Bearing: Acts as a foundational Step-1 Complete SYSADOA to halt joint space narrowing and aggressively restore chondrocyte vitality.
Lumbar Spondylosis (Facet-Joint Architecture): Preserves spinal cartilage integrity while providing targeted 5-LOX modulation to resolve localized spinal inflammation and chronic back pain.
Rheumatoid Arthritis (The NSAID-Sparing Adjunct): Serves as a potent NSAID-sparing shield by down-regulating leukotriene-induced synovial swelling without compounding toxic daily analgesic burdens.
Clinical Efficacy vs. Standard Care: Unlike chronic NSAIDs which trigger the 5-LOX “NSAID Shunt” (exacerbating swelling) and risk gastric erosion or AKI, BON-WAC guarantees 100% gastro-mucosal and renal safety. Furthermore, it provides complete matrix rebuilding substrates with zero diarrheal or hepatotoxic liabilities, unlike Diacerein.
| Active Substance | Strength per Unit |
|---|---|
| Glucosamine Sulphate | 500mg |
| Chondroitin Sulphate 100mg | - |
| Methylsulfonylmethane | 200mg |
| Boswellia Serrata API | 50mg |
| Curcumin USP | 50mg |
* Excipients and coating agents not listed. Refer to full SMPC for complete profile.
Acute / Loading Dose (Weeks 1-4): 1 Tablet Three Times Daily (TDS). This rapidly saturates the joint matrix with structural substrates and establishes an optimal baseline of 5-LOX modulation to halt acute inflammatory flare-ups.
Maintenance Dose (Months 2-6): 1 Tablet Twice Daily (BID). A minimum 3-month continuous cycle is pharmacologically required for complete structural Type II collagen cross-linking and long-term joint preservation.
Administration Requirement: Must be administered strictly with or immediately after lipid-containing meals to maximize absorption.
Absolute Contraindications: Strictly contraindicated in patients with active biliary obstruction (symptomatic gallstones) due to the cholagogue properties of Curcumin.
Drug Interactions: May exert synergistic pharmacodynamic effects with Vitamin K Antagonists (e.g., Warfarin); clinicians should monitor INR closely during concurrent therapy.
Shadman Khalil –
Bon-Wac has been a game-changer for my joint health. After consistent use, I’ve noticed a significant reduction in discomfort and an improvement in mobility. It’s reassuring to know that the product meets high-quality standards with GMP, DRAP, and Halal certifications.
Sobaina Mujeeb –
I got this for my mom, and the results have been Amazing. Before trying em on wax D, we tried a lot of different medications but nothing quite worked like Bon wac d. Ever since my mom started taking it, it’s like she has forgotten all abt her knee Osteoarthritis